江苏省“青蓝工程”优秀骨干教师培养对象，ios版雷竞技官网“钟山学术新秀”和“133”优秀骨干教师。中国畜牧兽医学会中兽医分会副秘书长，华东地区中兽医学研究会常务理事，江苏省中西兽医结合研究会常务理事。主持国家自然科学基金3项、国家科技支撑项目子课题、公益性（农业）行业项目子课题、教育部科学技术重点项目、中央高校基本科研业务费专项资金等项目各1项，参加4项国家自然基金项目的研究。自工作以来，在国内外核心期刊上发表研究性论文100多篇，其中SCI收录论文88篇，近五年发表论文60余篇，其中以第一作者和通讯作者发表SCI收录论文27篇；作为第一申报人获得授权发明专利3项，申报专利3项；以主要参加人获得国家发明专利6项、新兽药2项；主编、副主编著作4部，参编著作10部。

研究方向：中兽医与中兽药对畜禽疾病的防治；中兽医研发；

科研项目：

（一）纵向项目

1. 国家自然科学基金面上项目，32373053，地黄多糖树枝状介孔二氧化硅-脂质复合体多组分佐剂的构建及其佐剂作用机理的研究，2024/01-2027/12，直接经费50万，在研，主持。

2. 十四五国家重点研发计划，课题主持人，中兽药现代化与产业化技术研发（2022YFD1801103），2022.11至2025.12，371万，在研，主持。

3. 国家自然科学基金面上项目，32072905，中药多糖Pickering乳液的佐剂活性及其作用机理的研究，2021.01至2024.12，直接经费58万，在研，主持。

4. 国家自然科学基金面上项目，31872509，阳离子修饰多糖聚乳酸羟基乙酸共聚物纳米粒的佐剂活性及其作用机理的研究，2019-01至2022-12，直接经费59万，在研，主持。

5. 国家自然科学基金面上项目，31672596，多糖脂质立方液晶纳米粒佐剂活性及对树突状细胞作用分子机理的研究，2017/01-2020/12，直接经费62万，在研，主持。

6. 国家自然科学基金面上项目，31372472，纳米化提高中药成分脂质体的免疫增强作用和机理的研究，2014/01-2017/12，80万，已结题，主持。

7. 行业公益性项目，201303046-09，动物疫苗制剂及下游工艺技术研究与示范子课题，2013/01-2017/12，218万，已结题，主持。

8. 国家自然科学基金青年基金，30901085，应用脂质体技术提高中药成分的免疫增强作用和机理研究，2010/01-2012/12，20万，已结题，主持。

9. 国家科技支撑项目，2008BADB4B06，中兽药免疫增强剂及疫苗佐剂的研制与开发—子课题，2008/01-2010/12，20万，已结题，主持。

10. 中央高校基本业务费---科研业务专项，KYZ201117，新型皂苷纳米脂质体免疫增强剂的研制及应用，2011/01-2013/12，40万，已结题，主持。

11. 教育部科学技术重点项目，108153，抗新城疫病毒中药成分的导向分离及分子修饰研究，2008/01-2010/12，10万，已结题，主持。

12. 公益性行业（农业）科研专项经费，201403051，中兽医关键技术研究与示范，2014/01-2018/12，1557万，在研，参加（3/10）。

（二）横向项目（企业合作项目）

1. 甘胆口服液的药理机制研究，合作企业：北京生泰尔科技股份有限公司；

2. 葛根芩连片和健胃消食片的药理作用机制的研究，合作企业：北京生泰尔科技股份有限共公司；

3. 防治猪肺热咳喘证的中兽药开发，合作企业：郑州福源药业有限公司；

4. 改善犬猫胃肠道功能的植物提取物的研发，合作企业：乖宝宠物集团。

5. 防治犬猫口炎的植物提取物的开发，合作企业：乖宝宠物集团。

6. 与乖宝宠物食品集团股份有限公司共建“Barf自然食谱产业研究院”，合作企业：乖宝宠物集团。

7. 防止牛肺热咳喘的中兽药研发，合作企业：齐鲁晟华制药有限公司。

8. 复方马坡沙星喷剂对猫假中间葡萄球菌及马拉色菌引起混合感染的药效评价试验，合作企业：源天生物医药科技（佛山）有限公司。

9. 氟雷拉纳滴剂对猫感染蜱虫的药效评价临床试验，合作企业：佛山市南海东方澳龙制药有限公司。

10. 麻杏石甘口服液对猫肺热咳喘证的药效评价临床试验，合作企业：麦里生物科技（上海）有限公司。

11. 益生菌产品对大肠杆菌O₇₈攻毒肉鸡的预防及保护作用研究，合作企业：蓝星安迪苏南京有限公司。

荣誉奖项：

1. 2012年入选江苏省“青蓝工程”优秀青年骨干教师；

2. 2012年入选ios版雷竞技官网“钟山学者——钟山学术新秀”；

3. 2022年入选江苏省“333高层次人才”第三层次培养对象。

获奖及发明专利：

1. 2018年江苏省科学技术奖（二等奖）：分子修饰和新剂型提高中药成分的生物活性及其机理及新型免疫增强剂的研究，2/9。（胡元亮、王德云、刘家国、范云鹏、郭利伟、王洪超、孔祥峰、孙峻岭、卢宇）。

2. 专利：王德云，邓翔文，李奎，于亚明，武志勇，朱少武，施宗傲，常广军，一种中药组合物及其制备方法与在制备防治牛呼吸道疾病产品中的应，2024年03月22日，专利 号： ZL 2023113479085.

3. 专利：王德云，孔祥瑞，卢炫圻，武志勇，朱少武，施宗傲，刘振广，杨阳，一种防治犬猫腹泻的中药组方片剂及其制备方法与应用，2024年03月22日，专利号：ZL 2023 1 1469585.7.

4. 专利：王德云，郭雪文，武志勇，朱少武，施宗傲，于亚明，一种中药组合物及其制备方法与在制备提高母猪泌乳产品中的应用，2024年01月30日，专利 号： ZL 2023 1 0991868.1.

5. 专利：王德云，孔祥峰，胡新，武志勇，周子晖，朱少武，一种提高蛋鸡生产性能的中药组合物及其制备方法与应用，2023年2月14日，专利号：ZL 202111506235.4

6. 专利：王德云，彭松，武志勇，朱少武，刘振广，杨阳，一种防治畜禽呼吸道综合征的中药组合物及其制备方法与应用，2022年5月24日，专利号：ZL 202111431349.7.

7. 专利：王德云，杨阳，武志勇，朱少武，刘振广，一种防治蛋鸡输卵管炎的中药组合物及其制备工艺与应用，2022年5月17日，专利号：ZL 202111428854.6.

8.  专利：王德云，武志勇，刘振广，朱少武，一种替代抗生素的中药复方饲料添加剂及其制备方法与应用，2022年4月22日，专利号：ZL202010500718.2。

10. 专利：王德云，朱少武，武志勇，刘振广，胡元亮，刘家国，一种防治畜禽腹泻的中药复方及其制备工艺，2021年05月28日，专利号：ZL 201810787483.2。

11. 专利：王德云，李友英，武志勇，朱少武，蔡高峰，蓝岚，潘瑶. 一种中药组合物及其制备方法与在预防腹泻或抗腹泻中的应用，2022年02月11日，专利号：ZL202110613153.3。

12. 专利：王德云，武志勇，刘振广，朱少武. 一种防治畜禽冷应激的复方制剂及其制备方法与应用，2021年10月26号，专利号： ZL202010685137.0。

13. 专利：王德云，郑思思，伯若楠，罗莉，胡元亮，刘家国，一种茯苓多糖聚乳酸纳米乳及其制备方法与应用，2019年01月25日授权，专利号：ZL 201610473811.2。

14. 专利：王德云，刘振广，伯若楠，胡元亮，刘家国，武毅 一种灵芝多糖脂质立方液晶及其制备方法与应用，2019年02月19日授权，专利号：ZL201610328083.6。

15. 专利：王德云，罗莉，郑思思，胡元亮，刘家国，武毅 一种山药多糖聚乳酸羟基乙酸纳米粒及其制备方法与应用，2019年02月22日授权，专利号：ZL 201610475169.1

16. 专利：王德云，邢杰，刘振广，伯若楠，胡元亮，刘家国，武毅. 一种香菇多糖修饰的碳纳米管及其制备方法与应用，2018年10月23日授权，专利号：ZL 201610475258.6。

17. 专利：王德云，卢宇，潘华荣，赵晓娟，胡元亮，侯继波，一种硫酸脂化聚蔗糖及其应用，2016年06月15日授权，专利号：ZL 201410346252.X。

18. 专利：王德云，袁菊，胡元亮，刘家国，范云鹏，赵晓娟，黄叶娥，一种提高畜禽免疫功能的蜂胶黄酮脂质体及其制备方法，2014年12月10日授权，专利号：ZL 201210203668.7。

19. 专利：王德云，黄叶娥，胡元亮，刘家国，余韵，陶阳，武毅，一种地黄多糖脂质体的制备方法，2014年12月10日授权，专利号：ZL 201310456446.0。

20. 专利：胡元亮，王德云，郭利伟，刘家国，张宝康，中药芪藿糖免疫增强剂，2012年08月22日授权，专利号：ZL 201010211999.6。

21. 新兽药注册证书：芪藿注射液，证号：（2013）新兽药证字38号。

22. 新兽药注册证书：藿蜂注射液，证号：（2013）新兽药证字8号。

23. 新兽药注册证书：芪藿散，证号：（2017）新兽药证字36号。

24. 新兽药注册证书：藿蜂散，证号：（2020）新兽药证字36号。

25. 新兽药注册证书：黄连解毒散，证号：（2017）新兽药证字14号。

26. 新兽药注册证书：苦地止痢散，证号：（2025）新兽药证字46号。

近年代表性论著： *为通讯作者。

1.        Jin He, Xuanqi Lu, Ningning Mao, Tianyu Zhu, Lin Yu, Yaming Yu, Song Pen, Xiangwen Deng, Bing Hu, Wenming Jiang, Yu Lu,*, Deyun Wang*. Cistanche deserticola polysaccharide- functionalized dendritic fibrous nano-silica - based adjuvant for H9N2 oral vaccine enhance systemic and mucosal immunity in chickens[J]. International Journal of Pharmaceutics 660 (2024) 124318

2.       Jin He, Tianyu Zhu, Ningning Mao, Gaofeng Cai, Pengei Gu, Zuchen Song, Xuanqi Lu, Yang Yang, Deyun Wang*, Cistanche deserticola polysaccharide-functionalized dendritic fibrous nano-silica as oral vaccine adjuvant delivery enhancing both the mucosal and systemic immunity[J]. International Journal of Biological Macromolecules 262 (2024) 129982.

3.        Ningning Mao, Yaming Yu, Jiqin Cui, Jin He, Yang Yang, Deyun Wang*, Effect of Matrine on growth performance, gut health, and gut microbiota in
chickens infected with avian pathogenic Escherichia coli[J]. Poultry Science, 104 (2025) 104520.

4.        Ningning Mao Yaming Yu, Xuanqi Lu, Yang Yang, Zhenguang Liu, Deyun Wang*, Preventive effects of matrine on LPS-induced inflammation in RAW 264.7 cells and intestinal damage in mice through the TLR4/NF-κB/MAPK pathway[J]. International Immunopharmacology 143 (2024) 113432.

5.       Jin He, Tianyu Zhu, Ningning Mao, Wenming Jiang, Fangzhu Lin, Xuanqi Lu, Zhenzhen Gao, Yang Yang, Deyun Wang,* Cistanche deserticola polysaccharide-functionalized dendritic fibrous nano-silica as oral delivery system for H9N2 vaccine to promote systemic and mucosal immune response [J]. International Journal of Biological Macromolecules 282 (2024) 136690.

6.       Lin Yu, Fangzhu Lin, Yaming Yu, Xiangwen Deng, Xiaofeng Shi, Xuanqi Lu, Yu Lu, Deyun Wang*. Rehmannia glutinosa polysaccharides enhance intestinal immunity of mice through regulating the microbiota [J]. International Journal of Biological Macromolecules 283 (2024) 137878.

7.       Ningning Mao, Yaming Yu, Jin He, Yang Yang, Zhenguang Liu, Yu Lu,* and Deyun Wang ,*  Matrine Ameliorates DSS-Induced Colitis by Suppressing Inflammation, Modulating Oxidative Stress and Remodeling the Gut Microbiota[J]. International Journal of Molecular Sciences, 2024, 25, 6613.

8.       Yang Yang, Lin Yu, Tianyu Zhu, Shuwen Xu, Jin He, Ningning Mao, Zhenguang Liu, Deyun Wang*. Neuroprotective effects of Rehmannia glutinosa polysaccharide on chronic constant light (CCL)-induced oxidative stress and autophagic cell death via the AKT/mTOR pathway in mouse hippocampus and HT-22 cells[J]. International Journal of Biological Macromolecules 261 (2024) 129813.

9.       Song Peng, Xuanqi Lu, Fangzhu Lin, Ningning Mao, Lin Yu, Tianyu Zhu, Jing He, Yang Yang, Zhenguang Liu, and Deyun Wang*. Rosa laevigata Polysaccharides Ameliorate Dextran Sulfate Sodium-Induced Ulcerative Colitis of Beagles through Regulating Gut Microbiota [J]. Chem. Biodiversity 2024, 21, e202302102.

10.     Song Peng, Pengfei Gu, Ningning Mao, Lin Yu, Tianyu Zhu, Jin He, Yang Yang, Zhenguang Liu and Deyun Wang,*. Structural Characterization and In Vitro Anti-Inflammatory Activity of Polysaccharides Isolated from the Fruits of Rosa laevigata[J]. International Journal of Molecular Sciences,  2024, 25, 2133

11.     Yaming Yu, Ningning Mao, Lin Yu, Fangzhu Lin, Xiaofeng Shi, Xuanqi Lu, Yang Yang, Yu Lu, Deyun Wang*. YiMu-QingGong san alleviates lipopolysaccharide-induced endometritis in mice via inhibiting inflammation and oxidative stress through regulating macrophage polarization[J]. Journal of Ethnopharmacology 337 (2025) 118992.

12.     Yang Yang, Linjie Lv, Shanshan Shi, Gaofeng Cai, Lin Yu, Shuwen Xu, Tianyu Zhu, Xinyue Su, Ningning Mao, Yue Zhang, Song Peng, Jin He, Zhenguang Liu, Deyun Wang. Polysaccharide from walnut green husk alleviates liver inflammation and gluconeogenesis dysfunction by altering gut microbiota in ochratoxin A-induced mice[J]. Carbohydrate Polymers,2023,32215, 121362.

13.     Yang Yang, Lin Yu, Tianyu Zhu, Shuwen Xu, Jin He, Ningning Mao, Zhenguang Liu, Deyun Wang. Neuroprotective effects of Lycium barbarum polysaccharide on light-induced oxidative stress and mitochondrial damage via the Nrf2/HO-1 pathway in mouse hippocampal neurons.[J]. International journal of biological macromolecules, 2023, 14;251:126315.

14.     Yue Zhang , Tianyu Zhu, Shuwen Xu , Pengfei Gu , Gaofeng Cai , Song Peng , Zhenguang Liu , Yang Yang, Yuanliang Hu, Jiaguo Liu , Deyun Wang . Cationic Nanoparticle-Stabilized Vaccine Delivery System for the H9N2 Vaccine to Promote Immune Response in Chickens.[J]. Molecular pharmaceutics,2023. 20(3):1613-1623

15.     Shuwen Xu  , Zhiyong Wu , Gaofeng Cai , Yue Zhang  , Song Peng  , Lina Jiao  , Zhenguang Liu  , Yang Yang,Deyun Wang.Astragalus polysaccharides combined with simvastatin as an immunostimulant enhances the immune adjuvanticity of oil-in-water emulsion and immune responses in mice.[J]. Vaccine,2023, 41(10):1684-1693

16.     Gaofeng Cai  , Caihong Wu  , Tianyu Zhu , Song Peng , Shuwen Xu  , Yuanliang Hu  , Zhenguang Liu,Yang Yang,Deyun Wang. Structure of a Pueraria root polysaccharide and its immunoregulatory activity on T and B lymphocytes, macrophages, and immunosuppressive mice.[J]. International journal of biological macromolecules, 2023,1;230:123386.

17.   Xinxin Bai, Zian Feng, Song Peng, Tianyu Zhu, Lina Jiao, Ningning Mao, Pengfei Gu, Zhenguang Liu, Yang Yang, Deyun Wang*. Chitosan-modified Phellinus igniarius polysaccharide PLGA nanoparticles ameliorated inflammatory bowel disease. Biomater Adv. 2022;139:213002.

18.   Yue Zhang, Pengfei Gu, Lina Jiao, Jin He, Lin Yu, Zhenguang Liu, Yang Yang, Yuanliang Hu, Jiaguo Liu, Deyun Wang*. Chinese yam polysaccharides PLGA-stabilized Pickering emulsion as an adjuvant system for PCV- 2 vaccine to enhance immune response. Int J Biol Macromol. 2022;219:1034-1046. IF: 8.025

19.   Gaofeng Cai, Caihong Wu, Ningning Mao, Zuchen Song, Lin Yu, Tianyu Zhu, Song Peng, Yang Yang, Zhenguang Liu, Deyun Wang*. Isolation, purification and characterization of Pueraria lobata polysaccharide and its effects on intestinal function in cyclophosphamide-treated mice. Int J Biol Macromol. 2022;218:356-367. IF: 8.0025

20.   Gaofeng Cai, Yang Yang, Pengfei Gu, Kui Li, Wusiman Adelijiang, Tianyu Zhu, Zhenguang Liu, Deyun Wang*. The secretion of sIgA and dendritic cells activation in the intestinal of cyclophosphamide-induced immunosuppressed mice are regulated by Alhagi honey polysaccharides. Phytomedicine. 2022;103:154232.

21.   Yue Zhang, Zexiao Fan, Pengfei Gu, Ningning Mao, Song Peng, Zuchen Song, Zhenguang Liu, Yang Yang, Deyun Wang*. Pickering emulsion stabilized by Chinese Yam polysaccharides PLGA for enhanced humoral and cellular immune responses. Colloids Surf B Biointerfaces. 2022;218:112746.

22.   Yue Zhang, Lina Jiao, Zhiyong Wu, Pengfei Gu, Zian Feng, Shuwen Xu, Zhenguang Liu, Yang Yang, Deyun Wang*. Fabrication and characterization of Chinese yam polysaccharides PLGA nanoparticles stabilized Pickering emulsion as an efficient adjuvant. Int J Biol Macromol. 2022 Jun 1;209(Pt A):513-524.

23.   Pengfei Gu, Gaofeng Cai, Yang Yang, Yuanliang Hu, Jiaguo Liu, Deyun Wang*. Polyethylenimine-coated PLGA nanoparticles containing Angelica sinensis polysaccharide promote dendritic cells activation and associated molecular mechanisms. Int J Biol Macromol. 2022;207:559-569.

24.  Lina Jiao, Zhenguang Liu, Yue Zhang, Zian Feng, Pengfei Gu, Yee Huang, Jiaguo Liu, Yi Wu, Deyun Wang*. Lentinan PLGA-stabilized pickering emulsion for the enhanced vaccination. International Journal of Pharmaceutics. 2022;611:121348. IF: 6.510

25.     Shuwen Xu , Zi’an Feng , Yue Zhang , Haiyu Ni , Zhenguang Liu , Deyun Wang *  pH-responsive Astragalus polysaccharide-loaded PLGA nanoparticles as an adjuvant system to improve immune responses. International Journal of Biological Macromolecules 222 (2022) 1936–194

26.     [15] Gaofeng Cai, Ningning Mao, Pengfei Gu, Tianyu Zhu, Jin He, Song Peng, Yang Yang, Zhenguang Liu, Yuanliang Hu and Deyun Wang*  Effects of Alhagi Honey Polysaccharides as Feed Supplement on Intestine Function and Microbiome, Immune Function, and Growth Performance in Chicken. International Journal of Molecular Sciences. 2022, 23, 14332.

27.     Gaofeng Cai, Adelijiang Wusiman, Pengfei Gu, Ningning Mao, Shuwen Xu, Tianyu Zhu, Jin He, Zhenguang Liu, Deyun Wang*. Supplementation of Alhagi honey polysaccharides contributes to the improvement of the intestinal immunity regulating the structure of intestinal flora in mice. Food Funct. 2021;12(20):9693-9707.

28.     Zian Feng, Lina Jiao, Zhiyong Wu, Jiameng Xu, Pengfei Gu, Shuwen Xu, Zhenguang Liu, Yuanliang Hu, Jiaguo Liu, Yi Wu, Deyun Wang*. A Novel Nanomedicine Ameliorates Acute Inflammatory Bowel Disease by Regulating Macrophages and T-Cells. Mol Pharm. 2021;18(9):3484-3495.

29.     Gaofeng Cai, Yu Wu, Adelijiang Wusiman, Pengfei Gu, Ningning Mao, Shuwen Xu, Tianyu Zhu, Zian Feng, Zhenguang Liu, Deyun Wang*. Alhagi honey polysaccharides attenuate intestinal injury and immune suppression in cyclophosphamide-induced mice. Food Funct. 2021;12(15):6863-6877.

30.     Zian Feng, Song Peng, Zhiyong Wu, Lina Jiao, Shuwen Xu, Yu Wu, Zhenguang Liu, Yuanliang Hu, Jiaguo Liu, Yi Wu, Deyun Wang*. Ramulus mori polysaccharide-loaded PLGA nanoparticles and their anti-inflammatory effects in vivo. Int J Biol Macromol. 2021;182:2024-2036.

31.   Tianxin Qiu, Pengfei Gu, Adelijiang Wusiman, Haiyu Ni, Shuwen Xu, Yue Zhang, Tianyu Zhu, Jin He, Zhenguang Liu, Yuanliang Hu, Jiaguo Liu, Deyun Wang*. Immunoenhancement effects of chitosan-modified ginseng stem-leaf saponins-encapsulated cubosomes as an ajuvant. Colloids Surf B Biointerfaces. 2021;204:111799.

32.     Pengfei Gu, Yue Zhang, Gaofeng Cai, Zhenguang Liu, Yuanliang Hu, Jiaguo Liu, Deyun Wang*. Administration Routes of Polyethylenimine-Coated PLGA Nanoparticles Encapsulating Angelica Sinensis Polysaccharide Vaccine Delivery System Affect Immune Responses. Mol Pharm. 2021;18(6):2274-2284.

33.     Adelijiang Wusiman, Wenming Jiang, Lin Yu, Tianyu Zhu, Jin He, Zhenguang Liu, Ruonan Bo, Jiaguo Liu, Deyun Wang*. Cationic polymer-modified Alhagi honey polysaccharide PLGA nanoparticles as an adjuvant to induce strong and long-lasting immune responses. Int J Biol Macromol. 2021;177:370-382.

34.     Zhenguang Liu, Jin He, Tianyu Zhu, Cong Hu, Ruonan Bo, Adelijiang Wusiman, Yuanliang Hu, and Deyun Wang* . Lentinan-Functionalized Graphene Oxide Is an Effective Antigen Delivery System That Modulates Innate Immunity and Improves Adaptive Immunity[J]. ACS Appl. Mater. Interfaces 2020, 12, 39014−39023.  

35.     Zhenguang Liu, Lin Yu, Pengfei Gu, Ruonan Bo, Adelijiang Wusiman, Jiaguo Liu, Yuanliang Hu, Deyun Wang*. Preparation of lentinan-calcium carbonate microspheres and their application as vaccine adjuvants [J]. Carbohydrate Polymers 245 (2020) 116520.

36.     Yue Zhang, Pengfei Gu, Adelijiang Wusiman, Shuwen Xu, Haiyu Ni, Tianxin Qiu, Zhenguang Liu, Yuanliang Hu, Jiaguo Liu, Deyun Wang*.  The Immunoenhancement Effects of Polyethylenimine-Modified Chinese Yam Polysaccharide-Encapsulated PLGA Nanoparticles as an Adjuvant [J]. International Journal of Nanomedicine 2020:15 5527–5543. 

37.     Zhenguang Liu, Lin Yu, Pengfei Gu, Ruonan Bo, Shuwen Xu, Adelijiang Wusiman, Jiaguo Liu, Yuanliang Hu, Deyun Wang*. Surface-Engineered Cubosomes Serve as a Novel Vaccine Adjuvant to Modulate Innate Immunity and Improve Adaptive Immunity in vivo[J]. International Journal of Nanomedicine 2020:15, 8595–8608. 

38.     Zhenguang Liu, Haiyu Ni, Lin Yu, Shuwen Xu, Ruonan Bo, Tianxin Qiu, Pengfei Gu, TianYu Zhu, Jin He, Adelijiang Wusiman, Shaowu Zhu, Jiaguo Liu, Yuanliang Hu, Deyun Wang⁎. Adjuvant activities of CTAB-modified Polygonatum sibiricum polysaccharide cubosomes on immune responses to ovalbumin in mice [J]. Int J Biol Macromol. 148 (2020) 793–801.

39.     Pengfei Gu, Adelijiang Wusiman, Yue Zhang, Gaofeng Cai, Shuwen Xu, Shaowu Zhu, Zhenguang Liu, Yuanliang Hu, Jiaguo Liu, Deyun Wang,* Polyethylenimine-coated PLGA nanoparticles-encapsulated Angelica sinensis polysaccharide as an adjuvant for H9N2 vaccine to improve immune responses in chickens compared to Alum and oil-based adjuvants [J]. Veterinary Microbiology, 251(2020)108894.

40.     Jin He, Zhenguang Liu, Wenming Jiang, Tianyu Zhu, Adelijiang Wusiman, Pengfei Gu, Jiaguo Liu, Deyun Wang⁎. Immune-adjuvant activity of lentinan-modified calcium carbonate microparticles on a H5N1 vaccine [J]. International Journal of Biological Macromolecules163(2020) 1384–1392.

41.     Zhenguang Liu, Tianyu Zhu, Jin He, Yue Zhang, Pengfei Gu, Tianxin Qiu, Ruonan Bo, Yuanliang Hu, Jiaguo Liu, Deyun Wang*. Adjuvanticity of Ganoderma lucidum polysaccharide liposomes on porcine circovirus type-II in mice[J]. International Journal of Biological Macromolecules, 2019, 141: 1158–1164.

42.     Pengfei Gu, Zhenguang Liu, Yaqin Sun, Ning Ou, Yuanliang Hu, Jiaguo Liu, Yi Wu, Deyun Wang*. Angelica sinensis polysaccharide encapsulated into PLGA nanoparticles as a vaccine delivery and adjuvant system for ovalbumin to promote immune responses [J]. International Journal of Pharmaceutics, 2019, 554: 72–78.

43.     Adelijiang Wusiman, Pengfei Gu, Zhenguang Liu, Shuwen Xu, Yue Zhang, Yuanliang Hu, Jiaguo Liu, Deyun Wang*, Xiaoyan Huang. Cationic polymer modified PLGA nanoparticles encapsulating Alhagi honey polysaccharides as a vaccine delivery system for ovalbumin to improve immune responses [J]. International Journal of Nanomedicine 2019:14 3221–3234.

44.     Adelijiang Wusiman, Shuwen Xu, Haiyu Ni, Pengfei Gu, Zhenguang Liu, Yue Zhang, Tianxin Qiu, Yuanliang Hu, Jiaguo Liu, YiWu, Deyun Wang*, YuLu. Immunomodulatory effects of Alhagi honey polysaccharides encapsulated into PLGA nanoparticles [J]. Carbohydrate Polymers, 2019, 211: 217–226.  IF: 7.182.

45.     Adelijiang Wusiman, Jin He, Tianyu Zhu, Zhenguang Liu, Pengfei Gu, Yuanliang Hu, Jiaguo Liu, Deyun Wang^⁎. Macrophage immunomodulatory activity of the cationic polymer modified PLGA nanoparticles encapsulating Alhagi honey polysaccharide [J]. International Journal of Biological Macromolecules, 2019, 134: 730–739. IF: 5.162.

46.     Ruonan Bo, Zhenguang Liu, Jing Zhang, Pengfei Gu, Ning Ou, Yaqin Sun, Yuanliang Hu, Jiaguo Liu, Deyun Wang*. Mechanism of Lycium barbarum polysaccharides liposomes on activating murine dendritic cells [J]. Carbohydrate Polymers, 2019, 205: 540–549.  IF: 7.182.

47.     Haiyu Ni, Shuwen Xu, Pengfei Gu, Adelijiang wusiman, Yue Zhang, Tianxin Qiu, Zhenguang Liu, Han Ni, Yuanliang Hu, Jiaguo Liu, YiWu, Deyun Wang*. Optimization of preparation conditions for CTAB-modified Polygonatum sibiricum polysaccharide cubosomes using the response surface methodology and their effects on splenic lymphocytes [J]. International Journal of Pharmaceutics,2019, 559: 410–419.

48.     Shuwen Xu, Adelijiang Wusiman, Zhenguang Liu, PengfeiGu, HaiyuNi, Yue Zhang, Yuanliang Hu, Jiaguo Liu, YiWu, DeyunWang*. pH-responsive astragalus polysaccharides-loaded poly(lactic-co-glycolic acid) nanoparticles and their in vitro immunogenicity [J]. International Journal of Biological Macromolecules, 2019, 125: 865–875. IF: 5.162.

49.     Pengfei Gu, Adelijiang Wusiman, Siyuan Wang, Yue Zhang, Zhenguang Liu, Yuanliang Hu, Jiaguo Liu, Deyun Wang*. Polyethylenimine-coated PLGA nanoparticles-encapsulated Angelica sinensis polysaccharide as an adjuvant to enhance immune responses [J]. Carbohydrate Polymers, 2019, 223: 11512. IF: 7.182.

50.     Pengfei Gu, Adelijiang Wusiman, Yue Zhang, Zhenguang Liu, Ruonan Bo, Yuanliang Hu, Jiaguo Liu, Deyun Wang^*. Rational design of PLGA nanoparticle vaccine delivery systems to improve immune responses [J]. Molecular Pharmaceutics, 2019, 16, 5000−5012

51.     Ou Ning, Sun Yaqin, Zhou Shuzhen, Gu Pengfei, Liu Zhenguang, Bo Ruonan, Hu Yuanliang, Liu Jjiaguo, Wang Deyun*. Evaluation of optimum conditions for Achyranthes bidentata polysaccharides encapsulated in cubosomes and immunological activity in vitro. International Journal of Biological Macromolecule. 2018, 109:748-760.  IF: 5.162.

52.     Zheng Sisi, Qin Tao, Lu Yu, Huang Yifan, Luo Li, Liu Zhenguang, Bo Ruonan, Hu Yuanliang, Liu Jjiaguo, Wang Deyun*. Maturation of dendritic cells in vitro and immunological enhancement of mice in vivo by pachyman- and/or OVA-encapsulated poly(d,l-lactic acid) nanospheres. International Journal of Nanomedicine. 2018, 26;13:569-583.

53.     Zhenguang Liu, Yaqin Sun^,, Jing Zhang, Ning Ou, Pengfei Gu, Yuanliang Hu, Jiaguo Liu, Yi Wu, Deyun Wang^*. Immunopotentiation of Polysaccharides of Atractylodes macrocephala Koidz-loaded nanostructured lipid carriers as an adjuvant. International Journal of Biological Macromolecules, 2018, 120:  768-774. IF: 5.162.

54.     Gu Pengfei, Xu Shuwen, Zhou Shuzhen, Liu Zhenguang, Sun Yaqin, Ou Ning, Hu Yuanliang, Liu Jiaguo, Wu Yi, Wang Xianwei, Deyun Wang*. Optimization of angelica sinensis polysaccharide-loaded Poly (lactic-co-glycolicacid) nanoparticles by RSM and its immunological activity in vitro. International Journal of Biological Macromolecules, 2018,107:222-229.

55.     Yaqin Sun, Jing Zhang, Ruonan Bo, Ning Ou, Pengfei Gu, Zhenguang Liu, Yuanliang Hu, Jiaguo Liu, Yi Wu, Deyun Wang∗. Polysaccharides of Atractylodes macrocephala Koidz-loaded nanostructured lipid carriers: Optimization on conditions by RSM and immunological activity in vitro. Journal of Drug Delivery Science and Technology, 2018,44:305-313.

发表中文核心期刊

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