Hao Wen Liang

Personal Information
School/Department:College of Food Science & Technology
Name (English): Hao Wen Liang
Education Level: With Certificate of Graduation for Doctorate Study
Business Address: ios版雷竞技官网食品科技学院A211
Degree: Doctoral degree
Professional Title: Associate Professor
Alma Mater: 江南大学

Personal HonorMore

2021 江南大学优秀研究生

2022 博士研究生国家奖学金

2023 江南大学优秀毕业研究生

Profile

郝文亮，天津人，中共党员，江南大学博士，清华大学博士后，2025年11月入职ios版雷竞技官网食品科技学院，任副教授。研究兴趣：致力于微生物合成生物学方面的研究，主要包括开发可编程的细菌基因表达系统用于食品/工业酶高效生物制造、解决当前基因编辑/突变技术存在的共性问题并创制新型的基因编辑/突变技术、农业微生物的选育及其应用等。近年来，共发表学术论文10余篇，其中以第一（共一）身份发表SCI论文8篇，包括Advanced Science、Nucleic Acids Research、Chemical Science（自然指数期刊）、Synthetic and systems Biotechnology、Journal of Agricultural and Food Chemistry、Frontiers in Bioengineering and Biotechnology、Biotechnology Progress等。主持国家自然科学基金青年项目、中国博士后面上项目以及重点研发计划子课题等国家及省部级项目3项。获博士研究生国家奖学金，江南大学酿酒奖学金一等（非酿酒方向），江南大学博士研究生学业一等奖学金，江南大学优秀博士论文，优秀研究生等荣誉和称号。是Cell systems，Biotechnology Advances，Microbial Cell Factories，International Journal of Biological Macromolecules，New Biotechnology， Journal of Biological Engineering等多家期刊独立审稿人。

Paper Publications
Patents
Published Books

Wen-Liang, Hao; De-Zhi, Geng; Yu-Feng, Liu; Lai-Chuang, Han; Zhe-Min, Zhou; Wen-Jing, Cui.MicroDFBEST: A dCas12b-derived dual-function base editor with programmable editing characteristics for microbial genetic engineering,Synthetic and Systems Biotechnology,2025,11(0):161-171
Xin, Yuan; Wenliang, Hao; Chong, Zhang; Yizhi, Ji; Yi, Wang.Rapid detection of genotoxicity employing an engineered high-sensitivity and tight SOS-response biosensor in Escherichia coli MG1655,Synthetic and Systems Biotechnology,2025,11(0):117-126
Yufeng, Liu; Wenliang, Hao; Yabo, Liu; Jingyuan, Si; Yuanyi, Chen; Jing, Li; Wenge, Zheng; Jiantao, Jiao; Ting, Xie; Pingping, Zhou; Chunmei, Pan.Improving the Catalytic Activity of a Quinone-Dependent Dehydrogenase for Deoxynivalenol Detoxification by Engineering the Conformation of the N-Terminal Loop.,Journal of Agricultural and Food Chemistry,2025,73(41):26256-26265
Wenliang, Hao; Shihao, Yang; Yuou, Sheng; Chengfeng, Ye; Laichuang, Han; Zhemin, Zhou; Wenjing, Cui.Efficient expression of recombinant proteins in Bacillus subtilis using a rewired gene circuit of quorum sensing,Biotechnology Progress,2025,41(3):e70007
Wenliang, Hao; Wenjing, Cui; Zhongmei, Liu; Feiya, Suo; Yaokang, Wu; Laichuang, Han; Zhemin, Zhou.A New-Generation Base Editor with an Expanded Editing Window for Microbial Cell Evolution In Vivo Based on CRISPR‒Cas12b Engineering,Advanced Science,2024,11(22):e2309767

Educational Experience

Work Experience

scientific research awards

2017.9~2023.6
江南大学发酵工程 The graduate student is educated
2013.9~2017.6
山东建筑大学生物工程 UNDERGRADUATE EDUCATION

2023.9~2025.9
清华大学工业微生物育种

Research Group

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